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Which target is best for patients with Parkinson's disease? A meta-analysis of pallidal and subthalamic stimulation.

Wataru SakoYoshimichi MiyazakiYuishin IzumiRyuji Kaji
Published in: Journal of neurology, neurosurgery, and psychiatry (2014)
The effect of GPi DBS was similar to STN DBS except for depression, however, only three studies described depression as adverse events. We need additional randomised trials with direct comparison between targets based on unified scoring of adverse events.
Keyphrases
  • deep brain stimulation
  • parkinson disease
  • depressive symptoms
  • clinical trial
  • sleep quality
  • open label
  • double blind
  • study protocol
  • case control
  • physical activity