Flavivirus Infection Associated with Cerebrovascular Events.
Cassia Fernanda EstofoleteBruno H G A MilhimNathalia ZiniSamuel N ScamardiJoana D'Arc SelvanteNikos VasilakisMauricio Lacerda NogueiraPublished in: Viruses (2020)
Arthropod-borne viruses (arboviruses) of the genus Flavivirus are distributed globally and cause significant human disease and mortality annually. Flavivirus infections present a spectrum of clinical manifestations, ranging from asymptomatic to severe manifestations, including hemorrhage, encephalitis and death. Herein, we describe 3 case reports of cerebrovascular involvement in patients infected by dengue and Zika viruses in Sao Jose do Rio Preto, São Paulo State, Brazil, a hyperendemic area for arbovirus circulation, including dengue, yellow fever, chikungunya and Saint Louis encephalitis viruses. Our findings highlight the potential threat that unusual clinical manifestations may pose to arbovirus disease management and recovery.
Keyphrases
- aedes aegypti
- zika virus
- dengue virus
- end stage renal disease
- endothelial cells
- chronic kidney disease
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- type diabetes
- genetic diversity
- risk factors
- risk assessment
- early onset
- patient reported outcomes
- climate change
- drug induced
- patient reported