Circulating dimethylguanidino valeric acid, dietary factors, and risk of coronary heart disease.

Yoriko HeianzaXuan WangMinghao KouSaumya TiwariJeramie D WatrousKathryn M RexrodeMona AlotaibiMohit JainFrank B HuJoAnn E MansonXiang Li

Published in: Cardiovascular research (2024)

Higher levels of plasma DMGV, a metabolite reflecting unfavorable CHD-related dietary intakes, were associated with an increased risk of CHD. The unfavorable association was attenuated by cardiometabolic risk factor status. Our study underscores the potential importance of plasma DMGV as an early biomarker associated with diet and the long-term risk of CHD among women.

Keyphrases

risk factors
physical activity
polycystic ovary syndrome
weight loss
type diabetes
metabolic syndrome
pregnant women
human health
climate change