5-hydroxymethylcytosine is highly dynamic across human fetal brain development.

Helen SpiersEilis HannonLeonard C SchalkwykNicholas J BrayJonathan S Mill

Published in: BMC genomics (2017)

This study represents the first systematic analysis of dynamic changes in 5hmC across human neurodevelopment and highlights the potential importance of this modification in the human brain. A searchable database of our fetal brain 5hmC data is available as a resource to the research community at http://www.epigenomicslab.com/online-data-resources .

Keyphrases

endothelial cells
electronic health record
resting state
induced pluripotent stem cells
white matter
healthcare
mental health
big data
functional connectivity
multiple sclerosis
cerebral ischemia
data analysis