Recombinant Zoster Vaccine Is Efficacious and Safe in Frail Individuals.
Desmond CurranJoon H KimSean MatthewsChristophe DessartMyron J LevinLidia OostvogelsMegan E RileyKenneth E SchmaderAnthony L CunninghamShelly A McNeilAnne E SchuindMelissa K Andrewnull nullPublished in: Journal of the American Geriatrics Society (2020)
The relatively nonrestrictive inclusion/exclusion criteria in the parent ZOE studies resulted in a range of participants that included frail and pre-frail older adults. RZV significantly reduced the risk of herpes zoster across all frailty subgroups.
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