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Leptin Modifies the Rat Heart Performance Associated with Mitochondrial Dysfunction Independently of Its Prohypertrophic Effects.

Edna Berzabá-EvoliCecilia ZazuetaJarumi Hishel Cruz HernándezNancy Patricia Gómez-CrisóstomoIsela Esther Juárez-RojopErick Natividad De la Cruz-HernándezMartínez Abundis Eduardo
Published in: International journal of endocrinology (2018)
Our results support the role of leptin as a deleterious factor for cardiac function and indicates that mitochondrial dysfunction could be a trigger for cardiac hypertrophy and failure.
Keyphrases
  • heart failure
  • oxidative stress