Low level of antifungal resistance of Candida glabrata blood isolates in Turkey: Fluconazole minimum inhibitory concentration and FKS mutations can predict therapeutic failure.

Amir Arastehfar Farnaz DaneshniaMohammadreza SalehiMelike Yaşar Tuğrul Hoşbul Macit Ilkit Weihua Pan Ferry Hagen Nazli Pinar Arslan Hatice Türk-Dağı Suleyha Hilmioglu PolatDavid S PerlinCornelia Lass-Flörl

Published in: Mycoses (2020)

Antifungal susceptibility testing should be supplemented with HS-FKS sequencing to predict TF for echinocandins, whereas fluconazole MIC ≥ 32 µg/mL may predict TF. Recent emergence of C glabrata isolates associated with antifungal TF warrants future comprehensive prospective studies in Turkey.

Keyphrases

candida albicans
biofilm formation
single cell
current status
escherichia coli