Low level of antifungal resistance of Candida glabrata blood isolates in Turkey: Fluconazole minimum inhibitory concentration and FKS mutations can predict therapeutic failure.
Amir ArastehfarFarnaz DaneshniaMohammadreza SalehiMelike YaşarTuğrul HoşbulMacit IlkitWeihua PanFerry HagenNazli Pinar ArslanHatice Türk-DağıSuleyha Hilmioglu PolatDavid S PerlinCornelia Lass-FlörlPublished in: Mycoses (2020)
Antifungal susceptibility testing should be supplemented with HS-FKS sequencing to predict TF for echinocandins, whereas fluconazole MIC ≥ 32 µg/mL may predict TF. Recent emergence of C glabrata isolates associated with antifungal TF warrants future comprehensive prospective studies in Turkey.