Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis.
Benedikt LeyAri Winasti SatyagrahaHisni RahmatMichael E von FrickenNicholas M DouglasDaniel A PfefferFe Esperanza EspinoLorenz von SeidleinGisela HenriquesNwe Nwe OoDidier MénardSunil ParikhGermana BanconeAmalia KarahaliosRichard N PricePublished in: PLoS medicine (2019)
The CSG performed well at the 30% threshold. Its high NPV suggests that the test is suitable to guide PQ treatment, and the high LR+ and low LR- render the test suitable to confirm and exclude G6PDd. Further operational studies are needed to confirm the utility of the test in remote endemic settings.