Cortical lesion hotspots and association of subpial lesions with disability in multiple sclerosis.
Erin S BeckJosefina MaranzanoNicholas J LucianoPrasanna ParvathaneniStefano FilippiniMark MorrisonDaniel J SutoTianxia WuPeter van GelderenJacco Adrianus de ZwartSamson AntelDumitru FetcoJoan OhayonFrances AndradaYair MinaChevaz ThomasSteve JacobsonJeff DuynIrene CorteseSridar NarayananGovind NairPascal SatiDaniel S ReichPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
Cortical lesions are highly prevalent and are associated with disability and progressive disease. Subpial lesion burden is not strongly correlated with white matter lesions, suggesting differences in inflammation and repair mechanisms.