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Chronic exposure to Zearalenone leads to endometrial hyperplasia in CD-1 mice by altering the inflammatory markers.

Varsha SinghPayal MandalShweta Singh ChauhanIshrat Jahan Saifinull MarhabaP V SandeepPankaj JagdaleAnjaneya AyanurKausar Mahmood Ansari
Published in: Toxicology research (2024)
Our finding conclude that ZEA targets the uterus and cause inflammation due to increased levels of inflammatory cytokines and proliferation mediators, as well as systemic toxicity denoted by a strong binding affinity with serum proteins.
Keyphrases
  • oxidative stress
  • high fat diet induced
  • signaling pathway
  • endometrial cancer
  • drug induced
  • capillary electrophoresis
  • type diabetes
  • oxide nanoparticles