Disease presentation of 1312 childhood-onset systemic lupus erythematosus: influence of ethnicity.
Fernanda J FiorotAline G IslabãoRosa M PereiraMaria T TerreriClaudia Saad-MagalhãesGlaucia V NovakBeatriz C MolinariAna P SakamotoNadia E AikawaLucia M CamposOctavio A PeracchiSimone AppenzellerVirgínia P FerrianiMarco F SilvaAdriana R FonsecaFlávio R SztajnbokLuciana B PaimMelissa M FragaEunice M OkudaBlanca E BicaEvaldo G SenaAna J MoraesAna M RolimPaulo F SpellingIloite M ScheibelAndré S CavalcantiErica N MatosTeresa C RobazziLuciano J GuimarãesFlávia P SantosValeria C RamosMagda Carneiro-SampaioEloisa BonfáClovis Artur Almeida da Silvanull nullPublished in: Clinical rheumatology (2019)
Our study demonstrated that disease presentation severity of African-Latin American cSLE patients is comparable with Caucasian. Mucocutaneous manifestations and autoantibodies profile were the only distinctive features of the former group. The unique mixed background of Brazilian patients probably minimized race diversity spectrum of these patients. Key Points • Our study demonstrated that disease presentation severity of African-Latin American cSLE patients is comparable with Caucasian. • Mucocutaneous manifestations and autoantibodies profile were the only distinctive features of African-Latin American cSLE patients. • African-Latin American cSLE patients had more often anti-phospholipid antibodies and hypocomplementemia. • The unique mixed background of Brazilian patients probably minimized race diversity spectrum of these patients.