Erythropoietin Reduces Auto- and Alloantibodies by Inhibiting T Follicular Helper Cell Differentiation.

Chiara GuglielmoSofia BinChiara CantarelliSusan HartzellAndrea Angeletti Chiara DonadeiArun CumpelikLisa AndersonEvan CodyPeter T SageGaetano La MannaEnrico FiaccadoriPeter S HeegerPaolo Cravedi

Published in: Journal of the American Society of Nephrology : JASN (2021)

Our findings newly demonstrate that EPO inhibits TFH-dependent antibody formation, an observation with potential implications for treating antibody-mediated diseases, including those of the kidney.

Keyphrases

signaling pathway
regulatory t cells
dendritic cells
human health
climate change