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Novel Synthetic Analogues of 19(S/R)-Hydroxyeicosatetraenoic Acid Exhibit Noncompetitive Inhibitory Effect on the Activity of Cytochrome P450 1A1 and 1B1.

Sherif M ShoiebRambabu DakarapuJohn R FalckAyman O S Ei-Kadi
Published in: European journal of drug metabolism and pharmacokinetics (2021)
Therefore, the synthetic analogues of 19-HETE could be considered as a novel therapeutic approach in the treatment of cancer and CVD.
Keyphrases
  • molecular docking
  • papillary thyroid
  • squamous cell
  • squamous cell carcinoma
  • combination therapy
  • young adults
  • lymph node metastasis