Single-cell mRNA profiling reveals transcriptional heterogeneity among pancreatic circulating tumour cells.

Morten LapinKjersti TjensvollSatu OltedalMilind JavleRune SmaalandBjørnar GiljeOddmund Nordgård

Published in: BMC cancer (2017)

The analysis of single pancreatic circulating tumour cells identified distinct subpopulations and revealed elevated expression of transcripts relevant to the dissemination of circulating tumour cells to distant organ sites.

Keyphrases

single cell
induced apoptosis
cell cycle arrest
gene expression
endoplasmic reticulum stress
rna seq
cell death
oxidative stress
lymph node
cell proliferation
high throughput