Nanosecond pulsed electric fields enhanced chondrogenic potential of mesenchymal stem cells via JNK/CREB-STAT3 signaling pathway.

Tong NingJinsong GuoKun ZhangKejia LiJue ZhangZheng YangZi-Gang Ge

Published in: Stem cell research & therapy (2019)

This study demonstrates a unique approach of nsPEF treatment to potentiate the chondrogenic ability of MSCs through activation of JNK/CREB-STAT3 that could have translational potential for MSC-based cartilage regeneration.

Keyphrases

mesenchymal stem cells
signaling pathway
umbilical cord
induced apoptosis
bone marrow
cell death
cell proliferation
pi k akt
stem cells
cell therapy
human health
endoplasmic reticulum stress
extracellular matrix
risk assessment
climate change