Mathematical modeling of pneumococcal transmission dynamics in response to PCV13 infant vaccination in Germany predicts increasing IPD burden due to serotypes included in next-generation PCVs.

Matthias HornChristian TheilackerRalf SprengerChristof von EiffErnestine MaharJulia Schiffner-RoheMathias W PletzMark van der LindenMarkus Scholz

Published in: PloS one (2023)

We conclude that introduction of next-generation PCVs for adults may prevent a substantial and increasing proportion of adult IPDs, with PCV20 having the potential to provide the broadest protection against pneumococcal disease.

Keyphrases

risk factors
human health
risk assessment
climate change