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Cooperation and life history evolution help obligate parasites to circumvent host genetic deficiencies.

Zachary M BaileyCarolin Charlotte Wendling
Published in: Evolution; international journal of organic evolution (2020)
How do obligate parasites cope with hosts that lack genetic elements required for parasite replication? Gupta et. al. (2020) illustrate an experimental evolution system where lambda bacteriophages circumvent a defective gene network in their E. coli host (which initially made it impossible for them to replicate) through both intracellular cooperation and evolutionary changes in phage life-history traits.
Keyphrases
  • genome wide
  • plasmodium falciparum
  • copy number
  • dna methylation
  • escherichia coli
  • pseudomonas aeruginosa
  • reactive oxygen species
  • transcription factor
  • cystic fibrosis
  • toxoplasma gondii