Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis.
Pietro MaggiJens KuhleSabine SchädelinFranziska van der MeerMatthias WeigelRiccardo GalbuseraAmandine MathiasPo-Jui LuReza RahmanzadehPascal BenkertFrancesco La RosaMeritxell Bach CuadraPascal SatiMarie ThéaudinCaroline PotVincent van PeschDavid LeppertChristine StadelmannLudwig KapposRenaud Du PasquierDaniel S ReichMartina AbsintaCristina GranzieraPublished in: Neurology (2021)
Chronic white matter inflammation was associated with increased levels of sNfL and disease severity in nonacute MS, suggesting that PRL contribute to clinically relevant, inflammation-driven neurodegeneration.