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Analysis of the GSTP1 rs1695 polymorphism association with the development of asthma and phenotypic manifestations.

Guzel F MukhammadiyevaAkhat B BakirovDenis O KarimovMunira M ZiatdinovaYana V ValovaAlla I BorisovaAlbina A Distanova
Published in: The Journal of asthma : official journal of the Association for the Care of Asthma (2021)
These results suggest that the carriage of the A/A genotype of polymorphic locus rs1695 of the GSTP1 gene is a protective factor in the development of complications and an allergic reaction to house allergens among asthmatics, while the carriage of the G allele is associated with an increased risk for asthma complications.
Keyphrases
  • chronic obstructive pulmonary disease
  • allergic rhinitis
  • lung function
  • risk factors
  • gene expression
  • air pollution
  • dna methylation
  • transcription factor
  • atopic dermatitis