Association of the ZC3H11B, ZFHX1B and SNTB1 genes with myopia of different severities.

Shu Min TangFen Fen LiShi Yao LuKa Wai KamPancy O S TamClement Chee Yung ThamChi Pui PangJason C S YamGuy L J Chen

Published in: The British journal of ophthalmology (2019)

We confirmed ZC3H11B as a susceptibility gene for high and extreme myopia, and ZFHX1B and SNTB for extreme myopia in Chinese populations. Instead of myopia onset, these three genes were more likely to impose risks of progressing to high and extreme myopia.

Keyphrases

optic nerve
genome wide
climate change
genome wide identification
genome wide analysis
gene expression
dna methylation
copy number
human health
genetic diversity