Association of Early Hemodynamic Profile and the Development of Systolic Dysfunction Following Traumatic Brain Injury.
Vijay KrishnamoorthyAli Rowhani-RahbarNophanan ChaikittisilpaEdward F GibbonsFrederick P RivaraNancy R TemkinAlex QuistbergMonica S VavilalaPublished in: Neurocritical care (2018)
Patients who develop systolic dysfunction following TBI have a distinctive hemodynamic profile, with early hypertension and tachycardia, followed by a decrease in blood pressure over the first day after TBI. This profile suggests an early maladaptive catecholamine-excess state as a potential underlying mechanism of TBI-induced systolic dysfunction.