Comparison of vaginal microbiota in gynecologic cancer patients pre- and post-radiation therapy and healthy women.
Despina TsementziAngela Pena-GonzalezJinbing BaiYi-Juan HuPretesh PatelJoseph SheltonMary DolanJessica ArluckNamita KhannaLesley ConradIsabelle ScottTony Y EngKonstantinos T KonstantinidisDeborah W BrunerPublished in: Cancer medicine (2020)
This is among the first reports identifying VM changes among postmenopausal women with cancer. RT alone seems to affect several phylogroups (12 bacterial genera), while gynecological cancer and its treatment modalities are associated with even greater significant shifts in the vaginal microbiota including the enrichment of opportunistic bacterial pathogens, which warrants further attention.