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Genome-wide identification of replication fork stalling/pausing sites and the interplay between RNA Pol II transcription and DNA replication progression.

Patricia RojasJianming WangGiovanni GuglielmiMartina Mustè SadurnìLucas PavlouGeoffrey Ho Duen LeungVijay RajagopalFabian SpillMarco Saponaro
Published in: Genome biology (2024)
Altogether, our findings highlight how transcription and replication overlap during S-phase, with both positive and negative consequences for replication fork progression and genome stability by the coexistence of these two processes.
Keyphrases
  • genome wide identification
  • transcription factor
  • dna methylation
  • nucleic acid