Genome-wide identification of replication fork stalling/pausing sites and the interplay between RNA Pol II transcription and DNA replication progression.
Patricia RojasJianming WangGiovanni GuglielmiMartina Mustè SadurnìLucas PavlouGeoffrey Ho Duen LeungVijay RajagopalFabian SpillMarco SaponaroPublished in: Genome biology (2024)
Altogether, our findings highlight how transcription and replication overlap during S-phase, with both positive and negative consequences for replication fork progression and genome stability by the coexistence of these two processes.