Life's essential 8, genetic susceptibility, and risk of inflammatory bowel diseases: a population-based cohort study.

Honghao YangQing ChangChao JiGang ZhengZheng MaLiangkai ChenYang XiaYuhong Zhao

Published in: The international journal of behavioral nutrition and physical activity (2024)

Better CVH, defined by LE8, was associated with significantly lower risks of IBD, UC, and CD, irrespective of genetic predisposition. Our results underscore the importance of adherence to LE8 guidelines for maintaining CVH as a potential strategy in the prevention of IBD.

Keyphrases

genome wide
human health
copy number
ulcerative colitis
risk assessment
clinical practice
type diabetes
adipose tissue
dna methylation
climate change
skeletal muscle
insulin resistance