Defective Visceral Adipose Tissue Adaptation in Gestational Diabetes Mellitus.
Colm J McElwainSamprikta MannaAndrea MusumeciIsaac SylvesterChloé RouchonAnne Marie O'CallaghanMustafa Abdalla Bakhit EbadFergus P McCarthyCathal M McCarthyPublished in: The Journal of clinical endocrinology and metabolism (2023)
These findings suggest that GDM-obese pregnancy is specifically characterised by inadequate VAT remodelling and dysfunctional molecular signalling which contribute to insulin resistance and hinder metabolic health.
Keyphrases
- adipose tissue
- insulin resistance
- pregnancy outcomes
- high fat diet
- metabolic syndrome
- public health
- healthcare
- polycystic ovary syndrome
- pregnant women
- high fat diet induced
- preterm birth
- mental health
- type diabetes
- health information
- skeletal muscle
- glycemic control
- single molecule
- weight loss
- human health
- bariatric surgery