Mast cell-nerve interactions correlate with bloating and abdominal pain severity in patients with non-celiac gluten / wheat sensitivity.
Fiorella GiancolaUmberto VoltaRoberta RepossiRocco LatorreDorien BeeckmansFlorencia CarboneKaren Van den HouteFrancesca BiancoElena BonoraAlessandra GoriAnna CostanziniElisa BoschettiGiacomo CaioTim VanuytselVincenzo StanghelliniTack JanRoberto De GiorgioPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
Submucosal MC infiltration and the close (within 15 µm) MC-to-nerve proximity in the duodenum of NCG/WS patients are features providing a histopathological basis to better understand GI symptoms in this condition.