Prognostic factors of fungal infection in anti-melanoma differentiation-associated gene 5 antibody-positive associated interstitial lung disease.
Wanqing ZhouHaoran ChenTong JiRanxun ChenQingqing XuLulu ChenMin CaoHourong CaiJinghong DaiPublished in: Clinical rheumatology (2024)
Fungal infection is associated with an increased mortality in MDA5-ILD. The serum albumin level and corticosteroid dose should be taken into consideration when treating MDA5-ILD. Key Points • This study showed fungal infection is associated with an increased mortality in MDA5-ILD. In MDA5-ILD patients with fungal infection, the presence of decreased serum albumin level and high-dose corticosteroid therapy were identified as predictors for mortality.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- breast cancer cells
- prognostic factors
- high dose
- cardiovascular events
- risk factors
- cell cycle arrest
- stem cells
- low dose
- type diabetes
- gene expression
- genome wide
- copy number
- mesenchymal stem cells
- coronary artery disease
- transcription factor
- signaling pathway
- stem cell transplantation
- smoking cessation
- genome wide identification