Can glycated haemoglobin (HbA1c) be used as a predictor of left ventricular diastolic dysfunction in non-hypertensive patients with newly diagnosed type 2 diabetes mellitus: a cross-sectional study at a tertiary care centre in Eastern India.
Rajdeep PorelShyama ShyamaShaheen AhmadNeeraj KumarShamshad AhmadRatnadeep BiswasVishnu Shankar OjhaPublished in: BMJ open (2024)
This study demonstrated that age and HbA1c levels are independent predictors of LVDD in patients with newly diagnosed type 2 DM without hypertension. A cut-off value of 9.5% for HbA1c was identified with a high specificity and PPV for predicting LVDD in patients with newly diagnosed type 2 diabetes. This underscores the importance of conducting echocardiography in patients with newly diagnosed asymptomatic type 2 diabetes with HbA1c 9.5% or more to assess LVDD, allowing for prompt interventions if necessary and to decelerate the progression towards heart failure.
Keyphrases
- newly diagnosed
- left ventricular
- type diabetes
- heart failure
- glycemic control
- blood pressure
- tertiary care
- cardiac resynchronization therapy
- physical activity
- hypertrophic cardiomyopathy
- aortic stenosis
- acute myocardial infarction
- cardiovascular disease
- mitral valve
- insulin resistance
- computed tomography
- left atrial
- oxidative stress
- pulmonary hypertension
- risk factors
- metabolic syndrome
- ejection fraction
- weight loss
- aortic valve