Evaluation of the susceptibility test of polymyxin B using the commercial test Policimbac®.
Tanise Vendruscolo DalmolinMaiara Dos Santos CarneiroLuíza Peres de CastroFabiana Caroline Zempulski VolpatoPriscila Lamb WinkDaiana de Lima-MoralesAfonso Luís BarthPublished in: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] (2020)
Broth microdilution (BMD), the reference method to determine bacterial susceptibility to polymyxins, is a laborious and time-consuming technique. Policimbac® is a commercial test panel which uses lyophilized polymyxin B to determine the minimum inhibitory concentration for Gram-negative isolates. This study evaluated the performance of Policimbac® in comparison with BMD for 110 isolates. Although the Policimbac® presented a very low essential agreement, the categorical agreement with BMD was optimal. Policimbac® is an alternative approach to BMD for evaluating the susceptibility to polymyxin B.