Long-term statin therapy is associated with severe coronary artery calcification.
Kyari Sumayin NgamduDhairyasheel S GhosalkarHojune E ChungJared L ChristensenCadence LeeCelia A ButlerTiffany HoAlice ChuJacob R HeathMuhammad BaigWen-Chih WuGaurav ChoudharyAlan R MorrisonPublished in: PloS one (2023)
Long-term use of statins is associated with increased likelihood of severe CACS in patients with significant smoking history. The use of CACS to interpret cardiovascular event risk may require adjustment in the context of chronic statin therapy.