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Arachidonic Acid Cascade and Eicosanoid Production Are Elevated While LTC4 Synthase Modulates the Lipidomics Profile in the Brain of the HIVgp120-Transgenic Mouse Model of NeuroHIV.

Nina Y YuanRicky MaungZiying XuXianlin HanMarcus Kaul
Published in: Cells (2022)
Targeting the AA cascade may hold potential in the treatment of neuroinflammation observed in NeuroHIV and HANDs.
Keyphrases
  • mouse model
  • cerebral ischemia
  • traumatic brain injury
  • white matter
  • lipopolysaccharide induced
  • risk assessment
  • combination therapy
  • brain injury
  • subarachnoid hemorrhage
  • blood brain barrier
  • wild type