Predictive factors for simultaneous distant metastasis in head and neck cancer patients during the diagnostic work-up.
Carlos-Miguel Chiesa-EstombaMaria Soriano-ReixachEkhiñe Larruscain-SarasolaJon Alexander Sistiaga-SuarezJose Angel González-GarcíaAmaia Sanchez-MartinLaura Basterretxea-BadiolaNaiara SagastibeltaXabier Altuna-MariezcurrenaPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2021)
According to the present study, factors such as hypopharyngeal tumours, advanced T-stage, poor differentiation grade, have more than three positive lymph nodes, ECS and have a second primary tumour should be considered as high-risk indicators for screening. Based on these results, the authors recommend considered an extensive diagnostic work-up in all patients with a high risk of DM development.