Posttransplantation cyclophosphamide improves transplantation outcomes in patients with AML/MDS who are treated with checkpoint inhibitors.
Betül OranGuillermo Garcia ManeroRima M SalibaMansour AlfayezGheath Al-AtrashStefan O CiureaElias J JabbourRohtesh S MehtaUday R PopatFarhad RavandiAmin M AlousiTapan Mahendra KadiaMarina KonoplevaCourtney D D DiNardoKaty RezvaniElizabeth J ShpallPadmanee SharmaHagop M KantarjianRichard E ChamplinNaval G DaverPublished in: Cancer (2020)
The results of the current study indicated that HSCT with prior use of CPI appears feasible in patients with acute myeloid leukemia and/or myelodysplastic syndromes and the use of PTCy as GVHD prophylaxis improves outcomes.