The MDM2 inhibitor CGM097 combined with the BET inhibitor OTX015 induces cell death and inhibits tumor growth in models of neuroblastoma.
Tyler MaserJoseph ZagorskiShannon KellyAnna OstranderAustin GoodykeAbhinav NagulapallyJeffrey BondYeonhee ParkGiselle L Saulnier ShollerPublished in: Cancer medicine (2020)
This study warrants further investigation into the combination of MDM2 inhibitors and BET inhibitors for the treatment in NB.
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