Acute disseminated encephalomyelitis (ADEM) is an immune-mediated demyelinating disorder of the central nervous system which is usually precipitated by a viral infection or vaccination. A 3-month-old boy is reported who developed ADEM a week after full recovery from pertussis. MRI detected a high-intensity lesion extending from the pons to the mesencephalon, compatible with ADEM. Following the administration of intravenous immunoglobulins, the patient's clinical symptoms improved. This case report demonstrates that pertussis is capable of inducing an immune-mediated demyelinating disorder of the central nervous system.
Keyphrases
- high intensity
- case report
- liver failure
- respiratory failure
- resistance training
- drug induced
- aortic dissection
- magnetic resonance imaging
- cerebrospinal fluid
- hepatitis b virus
- high dose
- contrast enhanced
- clinical trial
- magnetic resonance
- computed tomography
- low dose
- sleep quality
- intensive care unit
- depressive symptoms