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Pivotal roles of tumor-draining lymph nodes in the abscopal effects from combined immunotherapy and radiotherapy.

Zhaoyun LiuZhiyong YuDawei ChenVivek VermaChenxi YuanMinglei WangFei WangQing FanXingwu WangYang LiYuequn MaMeng WuJin-Ming Yu
Published in: Cancer communications (London, England) (2022)
TDLN play a critical role in iRT by promoting the infiltration of CD8<sup>+</sup> T cells and maintaining the M1/M2 macrophage ratio.
Keyphrases
  • lymph node
  • early stage
  • adipose tissue
  • radiation therapy
  • locally advanced
  • radiation induced
  • neoadjuvant chemotherapy
  • rectal cancer