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Pulse-Controlled Amplification-A new powerful tool for on-site diagnostics under resource limited conditions.

Katharina MüllerSarah DaßenScott HolowachukKatrin ZwirglmaierJoachim StehrFederico BuersgensLars UllerichKilian Stoecker
Published in: PLoS neglected tropical diseases (2021)
PCA offers fast and decentralized molecular diagnostics and is applicable whenever rapid, on-site detection of infectious agents is needed, even under resource limited conditions. It combines the sensitivity and specificity of PCR with the rapidness and simplicity of hitherto existing rapid tests.
Keyphrases
  • loop mediated isothermal amplification
  • real time pcr
  • sensitive detection
  • label free
  • blood pressure
  • single molecule