Pulse-Controlled Amplification-A new powerful tool for on-site diagnostics under resource limited conditions.
Katharina MüllerSarah DaßenScott HolowachukKatrin ZwirglmaierJoachim StehrFederico BuersgensLars UllerichKilian StoeckerPublished in: PLoS neglected tropical diseases (2021)
PCA offers fast and decentralized molecular diagnostics and is applicable whenever rapid, on-site detection of infectious agents is needed, even under resource limited conditions. It combines the sensitivity and specificity of PCR with the rapidness and simplicity of hitherto existing rapid tests.