KLF6 negatively regulates HIF-1α in extravillous trophoblasts under hypoxia.
Ana C RaccaSofía NardiJésica Flores-MartinSusana Genti-RaimondiGraciela M Panzetta-Dutari
Published in: Placenta (2024)
Present results reveal that KLF6 contributes to a fine tune modulation of HIF-1α level under hypoxia. Thus, sustaining a HIF-1α homeostatic level, KLF6 might contribute to control EVT adaptation to hypoxia.