Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population.
Diana A van der PlaatJudith M VonkLies LahousseKim de JongAlen FaizIvana NedeljkovicNajaf AminCleo C van DiemenGuy G BrusselleYohan BosséCorry-Anke BrandsmaKe HaoPeter D ParéCornelia M van DuijnDirkje S PostmaH Marike BoezenPublished in: BMC pulmonary medicine (2019)
The definition of airflow obstruction and the population under study may be important determinants of which SNPs are associated with airflow obstruction. The genes FABP7 and NFYC(-AS1) could play a role in airflow obstruction in never-smokers specifically.