Oligosaccharides from agar extends lifespan through activation of unfolded protein response via SIR-2.1 in Caenorhabditis elegans.
Natsumi DesakaHitomi NishikawaYuji HondaKenji MatsumotoChiaki MatsuzakiKatsura MizushimaTomohisa TakagiYuji NaitoYasuki HigashimuraPublished in: European journal of nutrition (2022)
AGO delays the C. elegans aging process and extends their lifespan through the activations of ER-UPR and the IIS pathway.