Pentamidine Inhibits Titanium Particle-Induced Osteolysis In Vivo and Receptor Activator of Nuclear Factor-κB Ligand-Mediated Osteoclast Differentiation In Vitro.
Hye Jung IhnKiryeong KimHye-Sung ChoEui-Kyun ParkPublished in: Tissue engineering and regenerative medicine (2019)
These results indicate that pentamidine is effective in inhibiting osteoclast formation and significantly attenuates wear debris-induced bone loss in mice.