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Distinct trajectories of lung function from childhood to mid-adulthood.

Xian ZhangAndrew R GrayRobert J Hancox
Published in: Thorax (2024)
Lung function trajectories to mid-adult life are largely established before adolescence, with a few exceptions: a childhood airway hyper-responsiveness-related persistently low trajectory, which starts low and gets worse with age, and accelerated adult decline trajectories associated with smoking and obesity. Adverse trajectories are associated with a high risk of airflow obstruction in mid-adult life.
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