The heritability of BMI varies across the range of BMI-a heritability curve analysis in a twin cohort.
Francesca AzzoliniGeir D BerentsenHans J SkaugJacob V B HjelmborgJaakko A KaprioPublished in: International journal of obesity (2005) (2022)
We demonstrate that twin and molecular genetic studies need to consider how genetic effects vary across trait values. Such variation may reconcile findings of traits with high heritability and major differences in mean values between countries or over time.