Performance of two prognostic scores that incorporate genetic information to predict long-term outcomes following resection of colorectal cancer liver metastases: An external validation of the MD Anderson and JHH-MSK scores.
Kazunari SasakiJohan GagnièreAurélien DupréVictoria ArdilesJuan Manuel O'ConnorJaeyun WangAmika MoroDaisuke MoriokaStefan BuettnerLaurence GauMathieu RibeiroDoris WagnerNikolaos AndreatosInger Marie LøesFabian FitschekKlaus KaczirekPer Eystein LønningPeter KornpratGeorge PoultsidesCarsten KamphuesKatsunori ImaiHideo BabaItaru EndoChoon Hyuck David KwonFederico N AucejoEduardo de SantibañesMartin E KreisGeorgios Antonios MargonisPublished in: Journal of hepato-biliary-pancreatic sciences (2021)
In conclusion, using the largest and most heterogenous population of CRLM patients with known KRAS status, this independent, external validation demonstrated that the GAME score outperforms both the traditional Fong score and mCRS.