Utility of Homologous Recombination Deficiency Biomarkers Across Cancer Types.

Shiro Takamatsu J B Brown Ken Yamaguchi Junzo Hamanishi Koji Yamanoi Hisamitsu TakayaTomoko KaneyasuSeiichi MoriMasaki Mandai Noriomi Matsumura

Published in: JCO precision oncology (2022)

This study provides evidence for the usefulness of HRD analysis in all cancer types, improves chemotherapy decision making and its efficacy in clinical settings, and represents a substantial advancement in precision oncology.

Keyphrases

papillary thyroid
decision making
squamous cell
dna damage
dna repair
palliative care
lymph node metastasis
squamous cell carcinoma
childhood cancer
oxidative stress
young adults
replacement therapy
rectal cancer