Antipsychotic Discontinuation and New Trazodone Use in Ontario Nursing Homes: Evidence of Medication Substitution.
Daniel A HarrisLaura C MaclaganPriscila PequenoAndrea IaboniPeter C AustinLaura C RosellaJun GuanColleen J MaxwellSusan E BronskillPublished in: Journal of the American Medical Directors Association (2024)
Residents admitted to a nursing home with antipsychotic use had a higher rate of trazodone initiation if they discontinued (vs continued) an antipsychotic. These findings suggest antipsychotic substitution with trazodone after entering a nursing home.