Transcatheter versus surgical aortic valve replacement in lower-risk and higher-risk patients: a meta-analysis of randomized trials.
Yousif AhmadJames Philip HowardAhran D ArnoldMahesh V MadhavanChristopher M CookMaria C AluMichael J MackMichael J ReardonVinod H ThouraniSamir R KapadiaHans Gustav Hørsted ThyregodLars SondergaardTroels Højsgaard JørgensenWilliam D ToffNicolas M D A van MieghemRaj R MakkarJohn K ForrestMartin B LeonPublished in: European heart journal (2023)
In lower-risk patients, there was an early mortality reduction with TAVI, but no differences after later follow-up. There was also an early reduction in the composite of death or disabling stroke, with no difference at later follow-up. There were no significant differences for higher-risk patients. Informed therapy decisions may be more dependent on the temporality of events or secondary endpoints than the long-term occurrence of main clinical outcomes.