Neuronal RNA-binding protein dysfunction in multiple sclerosis cortex.
Hannah E SalapaCatherine HutchinsonBogdan F PopescuMichael C LevinPublished in: Annals of clinical and translational neurology (2020)
The discovery of hnRNP A1 and TDP-43 nucleocytoplasmic mislocalization in neurons in MS brain demonstrate that dysfunctional RBPs may play a role in neurodegeneration in MS, as they do in other neurological diseases.