Durable and dramatic response to checkpoint inhibition combined with COX-2 inhibitor celecoxib in a patient with p16+ metastatic sinonasal undifferentiated carcinoma: A case study.

Jonathan Q TrinhCassaundra AcostaArti EaswarRobert GalamagaAlan Tan

Published in: Cancer reports (Hoboken, N.J.) (2023)

Dual checkpoint inhibition deserves consideration when treating metastatic SNUC, especially after single agent therapy has failed. The positive effect of this treatment may be augmented by IDO1 inhibition.

Keyphrases

dna damage
squamous cell carcinoma
small cell lung cancer
cell cycle
case report
stem cells
oxidative stress
combination therapy
replacement therapy
smoking cessation