Pediatric oncology clinical trial participation where the geography is vast: Development of a clinical research system for tertiary and satellite centers in Ontario, Canada.
Sarah AlexanderMark GreenbergDavid MalkinCarol PortwineDonna L JohnstonMariana SilvaShayna ZelcerSamantha SonshineJanet ManzoCarla BennettKathy Brodeur-RobbCatherine DeveaultNivetha RamachandranPaul GibsonPublished in: Pediatric blood & cancer (2017)
Opportunities for participation in clinical trials are a core component of the care of children with cancer. In Ontario, many pediatric patients live long distances from their cancer center. This paper describes the work that was done in order to allow patients participating in Children's Oncology Group trials to receive care, including research protocol related care, jointly between the tertiary pediatric cancer center and the closer-to-home satellite center. The system is a pragmatic risk-based model, supporting excellence in care while ensuring good conduct of the research in compliance with applicable regulations and guidelines, including ethics oversight.
Keyphrases
- palliative care
- clinical trial
- healthcare
- papillary thyroid
- quality improvement
- squamous cell
- end stage renal disease
- childhood cancer
- physical activity
- pain management
- public health
- chronic kidney disease
- ejection fraction
- study protocol
- newly diagnosed
- squamous cell carcinoma
- phase ii
- big data
- deep learning
- artificial intelligence